Research | Personal

Welcome to the Research page of Eugene van Someren

My interest lies in Bioinformatics research (genetic network modeling) and stem cells (differentiation of human mesenchymal stem cells).

 

Contact details:

You can always contact me using the following email address, on my mobile or at home

Email: euscapone@gmail.com

GSM: +31 (6) 48755887

Home: +31 (10) 4753474

I am currently working at the st Radboud University in Nijmegen (CMBI-CDD), but can often be found at the pharmaceutical company Organon in Oss. You can also contact me at the office (see schedule below):

Tuesdays:

Wednesdays-Fridays:
Department

Dept. of Cell Biology and Applied Biology, Fac. of Natural Sciences

Molecular Design and Informatics
Institute/Company st. Radboud University N.V. Organon
Room Room 02.009 in Huygens building RK2326 in RK building
Address Toernooiveld 1 Molenstraat 110
Zip Code

6525 ED

5342 CC
City Nijmegen Oss
Country The Netherlands The Netherlands
Phone +31 (24) 3652523 +31 (412) 662298
Fax +31 (412) 662617
Email E.vanSomeren@science.ru.nl eugene.vansomeren@organon.com

 

 

Publications

See webpage of ICT group in Delft for more info about papers.

2006

  • E.P. van Someren, B.L.T. Vaes, W.T. Steegenga, A.M. Sijbers, K.J.Dechering, and M.J.T. Reinders, "Least absolute regression network analysis of the murine osteoblast differentiation network", bioinformatics, vol. 22, no. 4, pp. 477-484, 2006.
  • Maarten Clements (E.P. van Someren, T.A. Knijnenburg and M.J.T. Reinders thesis supervisors), "Discovery of co-regulated gene clusters by combining known transcription factor binding motifs and gene expression profiles", pp. 21, Delft University of Technology, april 2006.
  • Bart L.T. Vaes, Patricia Ducy, Anneke M. Sijbers, José M.A. Hendriks, Eugene P. van Someren, Nanning G. de Jong, Edwin R. van den Heuvel, Wiebe Olijve, Everardus J.J. van Zoelen, Koen J. Dechering, "Microarray analysis on Runx2-deficient mouse embryos reveals novel", Bone, no. 39, pp. 724– 738, 2006.

    2005

  • K.F. Au Yeung (E.P. van Someren and M.J.T. Reinders thesis supervisors), "A comparison between different optizimization techniques involving gradients to learn parameters from signoidal genetic network models", pp. 18, Delft University of Technology, january 2005.
  • B.L.T. Vaes, K.J. Dechering, E.P. van Someren, J.M.A. Hendriks, C.J.J.M. van de Ven, A. Feijen, C.L. Mummery, M.J.T. Reinders, W. Olijve, E.J.J. van Zoelen, W.T. Steegenga, "Microarray analysis reveals expression regulation of WNT antagonists in differentiating osteoblasts", Bone, vol. 36, no. 5, pp. 803-811, may 2005.
  • R.J.P. van Berlo, E.P. van Someren, and M.J.T. Reinders, "Studying the Conditions for Learning Dynamic Bayesian Networks to Discover Genetic Regulatory Networks", Eleventh annual conference of the Advanced School for Computing and Imaging, vol. (accepted for publication), Heijen, The Netherlands, June 8-10 2005.
  • E.P. van Someren, B.L.T. Vaes, W.T. Steegenga, A.M. Sijbers, K.J. Dechering, and M.J.T. Reinders, "Unravelling the murine osteoblast differentiation pathway by network structure analysis using time-series microarray data", IEEE Computational Systems Bioinformatics Conference, vol. (accepted for publication), Stanford, California, USA, August 8-12 2005.
  • E.P. van Someren and M.J.T. Reinders, "Which normalization method is best? A platform-independent biologically inspired quantitative comparison of normalization methods", IEEE Computational Systems Bioinformatics Conference, vol. (accepted for publication), Stanford, California, USA, August 8-12 2005.

    2004

  • M. van Roon (M.J.T. Reinders and E.P. van Someren thesis supervisors), "Genetic Network Models: Simulation and Inference Issues Concerning Knockout Data", M.Sc. Thesis, pp. 15, Delft University of Technology, 2004.
  • J. Lowijs (E.P. van Someren and M.J.T. Reinders), "Visualisation and significance analysis of several co-localisation techniques reveals clustering of cell-cycle related genes on the S. cerevisiae genome", M.Sc. Thesis, pp. 12, Delft University of Technology, August 2004.

    2003

  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders and E. Backer, "Multi-criterion optimization for genetic network modeling", Signal Processing, vol. 83, pp. 763-775, 2003.
  • R.J.P. van Berlo and E.P. van Someren and M.J.T. Reinders, "Studying the Conditions for Learning Dynamic Bayesian Networks to Discover Genetic Regulatory Networks", Simulation: Transactions of the society for modeling and simulation international, vol. 79, no. 12, pp. 689-702, December 2003.
  • E.P. van Someren (E. Backer and M.J.T. Reinders thesis supervisors), "Data-driven discovery of genetic network models", Ph.D. Thesis, ISBN 90-9016978, pp. 229, 2003.
  • E.P. van Someren and E. Backer and M.J.T. Reinders, "Genetic network modeling", Workshop on Dynamical Stochastic Modeling in Biology, pp. 88-99, Copenhagen, Denmark, Jan 2003.
  • R.J.P. van Berlo (E.P. van Someren and M.J.T. Reinders thesis supervisors), "Studying the Conditions for Learning Dynamic Bayesian Networks to Discover Genetic Regulatory Networks", M.Sc. Thesis, September 2003.

    2002

  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders and E. Backer, "On Genetic Network Modeling", Pharmacogenomics, vol. 3, no. 4, pp. 507-525, Ashley Publications Ltd, 2002.
  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders and E. Backer, "Regularization and noise injection for improving genetic network models", Computational and Statistical Approaches to Genomics., vol. Chap, pp. 211-226, Kluwer, 2002.
  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders and E. Backer, "Reverse Engineering of Genetic Networks through multi-criteria Optimization", SPIE-BIOS2002, Functional Monitoring and Drug-Tissue Interaction, ISBN 0-8194-4362-X, vol. 4623, pp. 47-58, San Jose, USA, Jan 2002.
  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders and E. Backer, "Searching for the structure of genetic networks", Eight annual conference of the Advanced School for Computing and Imaging, ISBN 90-803086-7-6, pp. 203-210, Lochem, The Netherlands, Jun 2002.

    2001

  • L.F.A. Wessels and E.P. van Someren and M.J.T. Reinders, "A Comparison of Genetic Network Models", Proceedings of the Pacific Symposium on Biocomputing, pp. 508-519, Hawai, Jan 2001.
  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders and E. Backer, "Searching for limited connectivity in genetic network models", Second International conference on systems biology, pp. 222-230, Pasedena, California, USA, Nov 2001.
  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders and E. Backer, "Robust Genetic Network Modeling by Adding Noisy Data", IEEE-EURASIP Workshop on Nonlinear Signal and Image Processing, Baltimore, Maryland, USA, June 2001.
  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders, "Genetic network models: A comparatie study", SPIE - BIOS 2001, MicroArrays: Optical Technologies and Informatics, vol. 4266, pp. 236-247, San Jose, USA, Jan 2001.
  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders and E. Backer, "Adding noise improves robustness of genetic network models", Seventh annual conference of the Advanced School for Computing and Imaging, pp. 407-415, Heijen, The Netherlands, May 2001.
  • M.J.T. Reinders and E.P. van Someren and L.F.A. Wessels, "Constrained genetic network by imposing robustness", Second Workshop on Computation of Biochemical Pathways and Genetic Networks, pp. 63-73, Villa Bosch, Heidelberg, Germany, June 2001.
  • J.C.A. van der Lubbe and E.P. van Someren and M.J.T. Reinders, "Dating and authentication of Rembrandt's etchings with the help of computational intelligence", International Cultural Heritage Informatics meeting, pp. 485-492, Milan, Italy, Sep 2001.
  • A.V. Alvarez (M.J.T. Reinders and E.P. van Someren thesis supervisors), "Modeling the Sparseness of Genetic Networks with a Genetic Algorithm", M.Sc. Thesis, pp. 13, Delft University of Technology, 2001.

    2000

  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders, "Linear modeling of genetic networks from experimental data", Eight International conference on Intelligent Systems for Molecular Biology, pp. 355-366, La Jolla, CA, USA, Aug 2000.
  • E.P. van Someren and L.F.A. Wessels and M.J.T. Reinders, "Information extraction for modeling gene expressions", 21st Symposium on Information Theory in the Benelux, pp. 215-222, Wassenaar, The Netherlands, May 2000.
  • J.C.A. van der Lubbe and E.P. van Someren and M.J.T. Reinders, "Computational intelligence for the dating and authentification of rembrandt’s etchings", ICSC Symposia on Intelligent Systems & Application, Dec 2000.

    1999

  • L.F.A. Wessels and E.P. van Someren and M.J.T. Reinders, "Information processing for intelligent molecular diagnosis", Pattern Recognition Letters, vol. 20, no. 11-13, pp. 1457-1465, Novemb 1999.
  • L.F.A. Wessels and E.P. van Someren and M.J.T. Reinders, "Mining gene expression data", Ninth Belgium-Dutch Conference on Machine Learning, Maastricht, The Netherlands, Nov 1999.
  • E.P. van Someren and M.J.T. Reinders, "Intelligent Molecular Diagnostic System", Fifth annual conference of the Advanced School for Computing and Imaging, pp. 184-188, Heijen, The Netherlands, July 1999.
  • E.P. van Someren and M.J.T. Reinders, "Consistent Tri-directional Reasoning with Human Concepts", Advanced Course in Artificial Intelligence, pp. 19-20, Chania, Greece, jULY 1999.

    Laatste wijziging op: 14-06-2007 10:52